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Opioids affect receptors in the brain and nervous system, altering pain signalling, influencing reward circuits and slowing central processes like breathing. While they are often prescribed in medical settings, they have powerful consequences on brain chemistry and a huge risk of dependence, addiction and overdose. This article explores how opioids work, how brain pathways adapt
Polysubstance abuse, more commonly referred to as polysubstance use, is when an individual takes two or more psychoactive substances within the same timeframe. This includes taking substances at the same time or consuming them close enough together so that their effects overlap. Whether accidental or intentional, combining substances creates highly unpredictable interactions, and over time
Whilst co-codamol is a common and readily available medication that people don’t consider dangerous, you should avoid drinking alcohol when taking it. Together, co-codamol and alcohol can increase sleepiness and other serious side effects. Whether you are taking pain medication, have already mixed the substances, or are concerned about family members, it’s important to know
Meow Meow is a street name commonly used for mephedrone, also known as 4-MMC or M-CAT. Despite being a drug with an amusing street name, it is a powerful stimulant, and it is not safe. Drugs are given names like this to be appealing. In this article, we’re going to take a closer look at
Ksalol is one of the many brand names for alprazolam, a benzodiazepine medication that is rarely prescribed by doctors in the UK. Like other drugs you might expect, such as heroin and cocaine, Ksalol and other benzodiazepines can be acquired on the street in illegal markets. Fake and illegal benzos are on the rise in
Abdominal pain after alcohol consumption could have a number of possible causes. In some cases, it can result from temporary digestive irritation after drinking, but it could also be a sign of a more serious medical condition. Factors including the location, severity and duration of the pain, as well as any accompanying symptoms, can help
Crystal meth is a powerful and highly addictive stimulant that can produce immediate physical and psychological effects alongside serious longer-term harms. In this article, we will look at the short- and long-term effects of crystal meth on the brain and body, as well as some of the risks associated with this drug… What Is
Amitriptyline is a commonly prescribed medication, with around 100,000 prescriptions being given out each year in the UK. People on prescription drugs may feel like other aspects of their life have to stop and often wonder, “Can you drink alcohol with amitriptyline?” While drinking alcohol whilst taking amitriptyline is not wholly discouraged by the NHS,
Co-codamol is a widely used and easily available medicine that combines two well-known painkilling ingredients – codeine and paracetamol. It is available over-the-counter (OTC) from pharmacies and also via prescription for stronger doses. It is precisely because it is so common and widely available that side effects from co-codamol can sometimes catch people off guard.
You might have heard of a type of drug commonly known as spice that has become increasingly prevalent in the UK. It’s gone from being called a ‘legal high’ to a strictly controlled Class B drug, and people often misunderstand its effects and potential risks. Because it’s a synthetic cannabinoid, it is sometimes compared to
